This week at the American Academy of Orthopedic Surgery meeting in San Diego, Mishra et al presented data that suggest PRP enhances mesenchymal stem cell proliferation. In their poster, mRNA results showed increased RUNX2, SOX-9 and aggrecan in PRP treated cell cultures versus control. This supports the use of PRP to augment microfracture cartilage restoration surgery. Clearly, further studies are needed but this is an important first step.
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