United Nations and Platelet Rich Plasma

AM at the United Nations

This week Dr. Allan Mishra presented his platelet rich plasma research at the United Nations in Geneva, Switzerland. The lecture was part of a worldwide conference on stem cells and regenerative medicine. Researchers, clinicians and government ministers from the United States, Dubai, Japan, Sinapore, Australia, Italy, France, Switzerland, the Netherlands, Spain, England, Turkey, Brazil and even Kazakhstan were in attendance.

The BioBridge meeting included the researchers from Kyoto Japan who are pioneering the use of induced pluripotential stem cells (an alternative to embryonic stem cells) and several physicians using platelet rich plasma (PRP) for dermatologic, traumatic and degenerative conditions. Data from the meeting suggests PRP is ahead of stem cells as a therapeutic biologic agent in terms of applications and safety.

The meeting was a collaborative and inspiring international event. The relationships established and the sharing of data will hopefully lead to future multi-disciplinary discoveries.

AM

Total Tendon

Apex PRP

Forbes Magazine Article Platelet Rich Plasma Tennis

Forbes just published an article on the use of platelet rich plasma (PRP) in elite athletes. It discusses the value of PRP in the context of cortisone and surgery. Forbes Story

To join in a group of patients and providers discussing the use of PRP and other treatments for tendon related injuries join the FREE Total Tendon Network.

Total Tendon, Tendon Tips, ApexPRP

Wired Magazine Stem Cells and PRP

Wired magazine just ran an article about stems and platelet rich plasma. Dr. Mishra's work is mentioned toward the end of the article.

Wired Stem Cell and PRP Article

Total Tendon

Join the FREE Total Tendon Network

San Francisco Chronicle Article: "Miracle Cure"

The San Francisco Chronicle calls platelet rich plasma a "Miracle Cure". To read the full story, click here.

Join the FREE Total Tendon Network to interact with patients and providers familar with platelet rich plasma as a treatment.

For more information:

Total Tendon, ApexPRP, Tendon Tips.com

Pioneer PRP Story on ABC TV

ABC TV in San Francisco just aired a story about the pioneering of platelet rich plasma for tendon related problems such as tennis elbow or patellar tendonitis.

Link to ABC TV Story about Stanford Football Player

To learn more about PRP visit: ApexPRP

Join the Total Tendon Network to have the most up to date information and interact with other patients and providers.

Total Tendon

How PRP works for Tendonitis and Tendon Tears

Platelet Rich Plasma produced by AM at Total Tendon

Platelet rich plasma (PRP) continues its advance as a novel and increasingly valuable treatment for tendon related problems like chronic tendonitis (also medically known as tendinosis). It is important to realize that not all physicians and machines produce clinically valuable (meaning it helps improve your pain and function) PRP. Published peered reviewed data suggests that PRP should contain at least 5 times the number of whole blood platelets.

(See Dr. Mishra's study published in American Journal of Sports Medicine Nov. 2006 for details)


As PRP evolves, it is important to find physicians and surgeons who base their clinical decisions on the literature not on opinion. Also, they should use devices that produce PRP with the appropriate concentrations of platelets. Not all methods are the same.

PRP Website: ApexPRP.com

Platelet rich plasma has been found to work via three mechanisms:

1. Release of Growth Factors increase local cell division (producing more cells)

2. Inhibition of excess inflammation (decreased early macrophage proliferation)

3. Recruitment of circulating or bone marrow derived cells that help repair tissue.

This combination of mechanisms helps heal a tendon. Animal data confirm that PRP helps produce a biomechanically stronger tendon.

All of these statements are based on peer reviewed publications.


AM

Total Tendon.com
ApexPRP.com

Platelet Rich Plasma and Rotator Cuff Repair

We now have published evidence that PRP is safe and may be useful in arthroscopic rotator cuff repair. This excellent study by Dr. Randelli and his colleagues will lead the way to larger trials.

Autologous platelet rich plasma for arthroscopic rotator cuff repair. A pilot study.

Here is Dr. Randelli's excellent rotator cuff video. (Thanks for sharing it.)

Randelli PS, Arrigoni P, Cabitza P, Volpi P, Maffulli N.

Dipartimento di Scienze Medico-Chirurgiche, Policlinico San Donato, Universita degli Studi di Milano, Milano.

Background and purpose. Arthroscopic repair of rotator cuff tears can produce excellent results. The application of platelet rich plasma during arthroscopic rotator cuff repair is safe, and produces results which do not deteriorate over time. Methods. A total of 14 patients undergoing arthroscopic repair of a rotator cuff tear received an intra-operative application of autologous platelet rich plasma in combination with an autologous thrombin component after tear repair. Following the procedure, patients were given a standardized rehabilitation protocol, and followed for 24 months. Outcome measures included a pain score (VAS) as well as functional scoring (UCLA and Constant scores). Results. Of the original 14 patients, 13 were seen at a final follow-up appointment 24 months after the index operation. Patients demonstrated a significant decrease in VAS scores and significant increases in the UCLA and Constant scores at 6, 12 and 24-month follow-ups compared to a pre-operative score. Conclusion. No adverse events related to this application were noted during the procedure. The application of platelet rich plasma during arthroscopic rotator cuff repair is safe and effective, and produces results which seem to be stable with time. A prospective randomized investigation will be necessary to ascertain the efficacy of platelet rich plasma application to improve or expedite the surgical outcome following arthroscopic rotator cuff repair.

Total Tendon

Apex PRP

Platelet Rich Plasma beats Cortisone

Gosens and Sluimer in a prospective, randomized controlled trial of 100 patients with tennis elbow found PRP beat cortisone in terms of improvement in pain and function at 24 weeks. This excellent study (Level 1 evidence) for the first time confirms platelet rich plasma performs better than the "gold standard" of treatment for patients with tennis elbow that don't respond to simple treatments.

Gosen and his colleagues will be hosting a "Trends in Tendinopathy" course next week in Europe. AM will be presenting and in this space, I will report the details of that important conference.

Total Tendon

ApexPRP.com

Platelet Rich Plasma Treats Stanford Football Player

A San Francisco based TV station just aired a segment on the use of platelet rich plasma to treat a Stanford football player. Here is a link to the spot.

Total Tendon

Apex PRP

Tendon Tips

PRP Used in Chronic Knee Tendonitis

Dr. Mishra's method of using platelet rich plasma to treat chronic knee tendonitis was discussed in a recent story about a college football Player. Here is a link to the story.

Please also visit our new website: Tendon Tips to view a story about Tiger Woods' recent knee surgery

Apex PRP.com

Total Tendon

Platelet Rich Plasma on TV in Los Angeles

A TV story on ABC7 in Los Angeles California just aired. The story discusses the value of using platelet rich plasma for chronic tennis elbow. It follows a patient who is an avid tennis player who was able to return to her game with a single PRP injection.

Link to TV Story

Apex PRP.com

Total Tendon.com