The use of PRP in shoulder is just beginning to emerge. Dr. Mishra published positive results in patients with chronic elbow tendonitis (AJSM 2006). The shoulder, however, is much more complex than the elbow. Multiple problems can accompany rotator cuff tendonitis including instability, AC arthritis (the joint between the shoulder and collar bone) and even overlapping pinch nerves in the neck from a disc herniation.
So, determining the value of PRP in shoulders will take more time. Basic science and cell cultures do support its use. Several investigators are evaluating it in patients. We look forward to prospective controlled trials to help us determine value.