Showing posts with label geron. Show all posts
Showing posts with label geron. Show all posts

Monday, October 11, 2010

Embryonic Stem Cells used to Treat Spinal Cord Injury Patient



For the first time in history, embryonic stem cells have been used to treat a patient with an acute spinal cord injury.  According to several reports the protocol calls for using the treatment within two weeks of the initial injury.  Geron, the company sponsoring the trial has spent years and tens of millions of dollars just to get to this first patient.  The hope is for this first phase that safety can be demonstrated.

We have officially entered the era of biologic medicine.  For quite some time there has been promise, now there is action.  It is hard to compute the amount of effort that has likely gone into getting to just this point.  It is the researchers and especially this first brave but tragic patient that deserve the credit for this advancement.

In the future, the use of either adult stem cells or induced pluripotent stem cells may become a better option.  For now, regardless of your stance on the ethics of embryonic stem cells this day must be marked as a milestone.

AM
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Friday, July 30, 2010

Trial of Embryonic Stem Cells for Spinal Cord Injury



The FDA lifted a hold on Geron's trial of embryonic stem cells to treat spinal cord injuries.  Geron hopes to begin the trial by the end of the year.  The specific cell line in use for this trial is GRNOPC1 which contains cells called oligodendrocyte progenitor cells. 

This is an interesting development.  Geron's stock popped 17% ($80-90 million in market cap) today on the news.  That speaks to the importance of a regulatory pathway for novel biologic treatments.  With the value in their stock, they can fund at least part of the trial.

Any thoughts out there on how to best fund new biologic treatments through the early clinical stages?

AM
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