Saturday, January 26, 2008

Total Tendon Network

A new network of both Patients and Providers has been created to improve the diagnosis and treatment of tendon related injuries and disorders. Discussion groups, pictures and video can be posted on this FREE network. Patients and Providers (Surgeons, Phyisicans, Physical Therapist etc) have joined from North America, Europe, South American, Australia and Asia.

Joining is simple and FREE.

Click here to sign up for the Total Tendon Network.

Brought to you by Total Tendon

Wednesday, January 16, 2008

American Academy of Orthopedic Surgery Article

Dr. Mishra's recent trip to Europe was featured in the American Academy of Orthopedic Surgery's Magazine: AAOS Now. The article titled "AAOS fellow takes European PRP Tour" was feature in the Jan. 2008 issue. The picture above is Dr. Mishra assisting on a platelet rich plasma enchanced achilles tendon repair in Sweden.

Click here to view AAOS Platelet Rich Plasma view article

Another sports medicine meeting in Chamonix France focusing on PRP will take place at the end of Jan 2008. Details of both meetings will be posted here soon.

Total Tendon

PRP Stimulates the greatest number of genes

According to recent reports from BEVA 2007, Cornell researchers examined the use of platelet-rich plasma (PRP) in horses with tendon injury, according to Schramme (Schnabel et al., Journal of Orthopedic Research, 2007). "The rationale is that if platelets release considerable growth factors, you could help with the healing of cartilage, tendons, ligaments)," he said.

"This study looked at gene expression patterns, DNA, and collagen content of equine tendon explants cultured (in vitro) with whole blood, plasma, and platelet-rich plasma," he continued. Concentrations of TGF-รข1 and PDGF were higher in PRP-treated tendons, compared to other blood products and bone marrow."

Schramme commented that all blood products stimulate gene expression, PRP seemed to stimulate the greatest number of genes (collagen types II and III, and COMP), with no c with no concomitant (accompanying) increase in molecules of harmful enzymes. "These findings support in vivo (in the live animal) investigation of 100% PRP as an autogenous (generated in the body), patient-side treatment for tendonitis," he noted. "It's another treatment that we need to carefully evaluate in vivo as it continues to come along.


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