Monday, August 31, 2009

Excellent Evidence for Platelet Rich Plasma (PRP)

Bosch et al in the Journal of Orthopedic Research just reported significant biomechanical evidence supporting the use of a single Platelet Rich Plasma injection for tendon injuries in an equine model. It is important to note this research was conducted using a formulation of platelet rich plasma contained about 4 times platelet concentration and 6 times white blood cell concentration. (Biomet Biologics GPS Device) The PRP was injected under ultrasound guidance.

Some PRP devices concentrate only platelets without any white blood cell concentration. This evidence and published human clinical data support the use of PRP that concentrate both. Make sure when considering a PRP procedure for tendon injuries to have the published literature guide treatment.

"The repair tissue in the PRP group showed a higher strength at failure (p = 0.021) and Elastic Modulus (p = 0.019). Histologically, PRP-treated tendons featured better organization of the collagen network (p = 0.031) and signs of increased metabolic activity (p = 0.031). It was concluded that PRP increases metabolic activity and seems to advance maturation of repair tissue over nontreated experimentally induced tendon lesions, which suggests that PRP might be beneficial in the treatment of clinical tendon injuries." See Full Abstract

Total Tendon


Anonymous said...

Hy Allan - That's Rogerio, from Brazil.
Here the PRP cases of tennis elbow and also those of Aquiles injuries are doing great. I hope that soon the procedure will be approved for rotine use. Any news from ClinicalTrials papers?
Warm regards from Brazil. Rogerio Teixeira Silva, MD

AM said...

Good to hear from you. When can I come visit your lovely country? The PRP trials are progressing well.


Anonymous said...

Nice post and this mail helped me alot in my college assignement. Say thank you you seeking your information.

Fitness/Sports Medicine Videos (4 million views)

Patient Application Form