Platelet-rich plasma comes in a variety of forms. Platelet-rich fibrin matrix (PRFM) is prepared by spinning blood and adding calcium to create a type of gel that can hold suture. In the study below, this gel was used in combination with a standard arthroscopic rotator cuff repair. No differences were seen in healing as measured by ultrasound at 6 and 12 weeks when the PRFM was added. There was also some suggestion that platelet rich fibrin matrix had a negative effect on healing.
It is crucial to understand that this data is specific to PRFM and not all types of platelet rich plasma. Most patients and even many providers fail to realize the importance of formulation and indications. PRP in the near future will become even more complex as newer formulations become available and as data matures.