Saturday, November 21, 2009

Platelet Rich Plasma and ACL Surgery

The use of Platelet Rich Plasma to augment anterior cruciate ligament reconstruction has been much discussed but not well studied until now. In a prospective randomized trial, Nin et al studied allograft ACL surgery with and without PRP.

"We prospectively randomized 100 patients undergoing arthroscopic patellar tendon allograft ACL reconstruction to a group in whom platelet-enriched gel was used (n = 50) and a non-gel group (n = 50). The platelet concentration was 837 x 10(3)/mm(3), and the gel was introduced inside the graft and the tibial tunnel. The use of PDGF, on the graft and inside the tibial tunnel, in patients treated with bone-patellar tendon-bone allografts has no discernable clinical or biomechanical effect at 2 years' follow-up." Read Full Abstract

This is a good example of where PRP may NOT be helpful.

AM
Total Tendon

1 comment:

Dr Amy said...

Hi Doc,
You left a comment on my site and suggested including some of your refs. I will do that. Your sites are full of excellent information I also have a larger site http://whiplash101.com and it would be great if you would consider adding a quest post there..it could of course link back to your sites

Let me know if this could work for you...I actually sent a couple of patients to your site

Best
Amy

HalfDome.TV
Fitness/Sports Medicine Videos (4 million views)

Patient Application Form