Everts et al (European Surgical Research: 2007) recently published their findings of the structure of platelet rich plasma. Their work is important because it will lead to a better understanding of how and when to use PRP. Further work about exactly how growth factors are released from both platelets and white blood cells is clearly needed. This important paper leads the way.
The picture above is from Evert's fine paper. The top picture is a platelet gel aggregate before the growth factors have been released. The bottom picture clearly shows the empty alpha granules indicating release of growth factors.
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